Material Safety Data Sheet for Arginine Malate

Identification

Product Name: Arginine Malate
Chemical Formula: C10H20N4O6
Common Synonyms: L-Arginine Malate, 2-Aminopentanedioic acid, L-Arg
CAS Number: 41373-95-1
Recommended Use: Nutritional supplement, research and laboratory reagent
Manufacturer Information: Listed on lab supply or industrial chemical labels with dedicated customer support and SDS request contacts
Emergency Contact: Refer to local poison control or official emergency response numbers

Hazard Identification

GHS Classification: Not classified as hazardous under GHS guidelines
Signal Word: None
Hazard Statements: No significant hazards identified in normal conditions; dust may cause mild respiratory irritation; contact with eyes or skin may cause slight irritation
Precautionary Statements: Avoid breathing dust; wash thoroughly after handling; wear appropriate personal protective equipment to limit exposure
Potential Health Effects: Dust inhalation might trigger coughing or slight discomfort in sensitive individuals; accidental eye contact may result in minor, reversible irritation; ingestion of laboratory quantities does not display acute toxicity, though excessive amounts should be avoided

Composition / Information on Ingredients

Chemical Name: L-Arginine Malate
Synonyms: L-Arginine mono malate, L-Arginine L-malic acid salt
PURITY: Typically 98-99% pure
Impurities: Trace amounts of water, possible residuals from synthesis such as L-Arginine, L-Malic acid, not expected to exceed limits for reagent grade materials
Molecular Weight: 292.28 g/mol

First Aid Measures

Inhalation: Move exposed person to fresh air; seek medical attention if symptoms linger; provide oxygen if breathing is affected
Skin Contact: Remove contaminated clothing; flush skin thoroughly with plenty of water and mild soap; medical attention if redness or discomfort persists
Eye Contact: Rinse eyes immediately with water for at least 15 minutes, lifting the upper and lower eyelids; call for medical assistance if irritation continues
Ingestion: Rinse mouth with water if conscious; avoid inducing vomiting; obtain advice from a doctor or poison control

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam; choose media appropriate for surrounding material
Hazards from Combustion Products: Combustion might generate nitrogen oxides and carbon oxides
Firefighting Instructions: Fire responders should wear self-contained breathing apparatus and full protective clothing
Special Protective Equipment: Full bunker gear and suitable chemical-resistant gloves
Unsuitable Extinguishing Media: None known

Accidental Release Measures

Personal Precautions: Use gloves and dust mask to avoid contact with skin, eyes, and airway exposure; keep unprotected personnel away
Environmental Precautions: Do not let large amounts enter sewers, drains, or environments where dilution is not possible
Clean-Up Methods: Sweep up spilled powder without raising dust, transfer to a clean, dry disposal container and seal; wash area with copious water after removal
Disposal: Dispose of according to local, regional, and federal regulations; residues must not contaminate groundwater or soil

Handling and Storage

Safe Handling: Avoid inhaling dust; prevent contact with skin and eyes; use with proper local exhaust; wash thoroughly after use; do not eat, drink, or smoke during handling
Storage Conditions: Store in a tightly closed original container; keep in a dry, well-ventilated place at ambient temperature; protect from excessive heat, sunlight, and moisture
Incompatible Materials: Strong oxidizers; acids and bases might degrade product quality over time
Packaging Materials: High-density polyethylene or glass recommended; containers should be labeled and remain sealed when not in use

Exposure Controls and Personal Protection

Engineering Controls: Well-ventilated workspace; if dust production exceeds safe limits, use local exhaust or laboratory fume hood
Occupational Exposure Limits: No established exposure limits for Arginine Malate; general nuisance dust limits apply (ACGIH TLV for particulate matter not otherwise regulated: 10 mg/m³ total dust)
Personal Protective Equipment: Safety glasses or goggles; nitrile gloves; lab coat; respiratory protection such as dust masks for heavy or prolonged dust exposure
Hygiene Measures: Wash hands thoroughly; avoid touching face, eyes, or mouth after handling; keep work area clean of residues

Physical and Chemical Properties

Physical State: Solid, crystalline powder
Color: White to off-white
Odor: Odorless or very faint
pH Value: 2.4-3.4 (5% solution in water)
Melting Point: Decomposes above 210°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water, sparingly soluble in ethanol
Vapor Pressure: Not volatile
Density: Approximately 1.45 g/cm³
Other Data: Stable under standard laboratory conditions; non-hygroscopic

Stability and Reactivity

Chemical Stability: Stable under routine storage and handling
Reactivity: Not highly reactive; avoid strong acids, bases, and oxidizers
Conditions to Avoid: Moisture, elevated temperature, prolonged exposure to air
Hazardous Reactions: No dangerous reactions known under normal use
Decomposition Products: Nitrogen oxides, carbon oxides

Toxicological Information

Acute Toxicity: Low toxicity expected; LD50 (oral, rat) estimated above 5000 mg/kg
Skin & Eye contact: May lead to transient mild irritation; no long-term effects reported
Inhalation: Inhaled dust can irritate nose, throat, or lungs if exposure is prolonged
Ingestion: Large doses could upset digestive system; small laboratory exposures considered safe
Sensitization: Not classified as a sensitizer
Carcinogenicity/Mutagenicity: Not listed as carcinogenic; no mutagenic effects noted in available studies
Other Effects: No reproductive toxicity or organ-specific toxicity has been reported

Ecological Information

Ecotoxicity: No significant toxicity identified for aquatic life or soil organisms at laboratory concentrations
Persistence and Biodegradability: Biodegradable; breaks down into basic amino acids/malate in the natural environment
Bioaccumulation Potential: Not expected to accumulate in living organisms
Soil Mobility: High mobility in water; very soluble and will leach if released in large amounts
Other: Avoid release of concentrated solutions into waterways to prevent added organic load or oxygen demand

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local and national regulations; suitable for landfill or incineration in approved facilities
Contaminated packaging: Rinse containers before disposal or recycling; unwashed packaging must be treated as chemical waste
Precautions: Prevent contact with soil, surface water, and sewer systems in raw form; do not pour large amounts down drains

Transport Information

UN Number: Not classified as hazardous for transport
Proper Shipping Name: Arginine Malate
Transport Hazard Class: Non-hazardous material
Packing Group: Not assigned
Marine Pollutant: No
Special Precautions: Avoid moisture ingress, prevent container damage or spillage during transit; conventional transport regulations apply

Regulatory Information

Regulatory Status: Not listed as a controlled or hazardous substance by US TSCA, EU REACH, or Canadian DSL
Labelling Requirements: Chemical identity and hazard warnings if applicable; follow occupational health regulations
SARA/OSHA Designations: Not subject to SARA Title III, not an OSHA hazardous chemical
EU Directives: Not classified as a hazardous material; comply with general chemical handling and hazard communication laws
Restrictions: National and international restrictions are not applicable to standard research, industrial, or supplement use