Product Name: Calcium Citrate
Chemical Formula: Ca3(C6H5O7)2·4H2O
CAS Number: 813-94-5
Synonyms: Tricalcium dicitrate, Citric acid calcium salt
Recommended Use: Dietary supplement, food additive, pharmaceutical applications
Supplier: Common chemical suppliers, pharmaceutical distributors, manufacturers specializing in mineral supplements
Contact Information: Resource depends on supplier, details on product label
Hazard Classes: Not classified as a hazardous substance according to GHS
Label Elements: No pictogram, signal word, or hazard statement required
Health Hazards: Dust may irritate respiratory tract if inhaled; eye contact may provoke mild irritation
Environmental Hazards: Low risk, large spill into water can affect local hardness
Physical Hazards: May present slipping hazard if spilled as powder
Routes of Exposure: Inhalation, ingestion, contact with eyes or skin
Substance: Calcium Citrate
Ingredients: Calcium Cation (Ca2+): 21-24% by weight, Citrate Anion: Around 76-79% by weight (includes water of hydration)
Purity: Typically above 98% pure in food/pharma forms
Impurities: Trace amounts of magnesium, sodium, and heavy metals (total heavy metals below 10 ppm typical for food grade)
Inhalation: Move to fresh air, monitor for persistent coughing; medical care for difficulty in breathing
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present, continue rinsing
Skin Contact: Rinse with water and mild soap, seek advice if irritation continues
Ingestion: Rinse mouth, give water to drink, large quantities contact medical professional; not considered toxic in intended dosages
General Information: Consult physician for further treatment, especially for known allergies or high exposure levels
Flammability: Not flammable
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or CO2 for surrounding fire
Unsuitable Media: None known for this substance
Combustion Products: Decomposition produces CO2, calcium oxide (irritant at high heat)
Protective Equipment: Standard gear for chemical fires; respirator for smoke
Firefighting Instructions: Isolate area, keep upwind of fire, use water to cool containers near flames
Personal Precautions: Evacuate unprotected people, wear dust mask, gloves, goggles
Environmental Precautions: Prevent runoff into sewers and waterways
Cleanup Methods: Sweep into containers, use wet methods to limit dust, ventilate area
Waste Disposal: Seal in labeled containers for proper handling, avoid raising airborne dust
Decontamination: Wash affected surfaces with water after sweeping
Handling: Avoid creating dust, use in ventilated areas, wash hands after use
Storage: Keep container tightly closed, store in cool, dry, and well-ventilated locations
Incompatible Materials: Strong acids or oxidizers may cause unwanted reactions or decomposition
Packaging: Use moisture-resistant containers, label with identification details
Industrial Practices: Rotate stock to use oldest product first, store off the ground
Occupational Exposure Limits: No strict limit for calcium citrate, but nuisance dust limits apply (e.g., OSHA PEL: 15 mg/m³ for total particulates)
Engineering Controls: Use local exhaust or general ventilation to maintain air quality
Personal Protective Equipment: Dust mask or respirator, safety goggles when dealing with powder, gloves for handling bulk quantities
Hygiene Measures: Wash hands after handling, remove contaminated clothing
Appearance: White, odorless, fine to granular powder
Odor: Odorless
pH (1% solution): 6.0–8.0
Solubility: Sparingly soluble in water (approx. 0.9g/L at 25°C), more soluble in dilute acids
Melting Point: Decomposes on heating above 120°C
Boiling Point: Not applicable (decomposes before boiling)
Density: About 1.63 g/cm³
Partition Coefficient: Not applicable
Vapor Pressure: Negligible
Other Properties: Stable under normal conditions, non-volatile, slightly hygroscopic
Chemical Stability: Stable under recommended conditions of storage and use
Hazardous Reactions: Reacts with strong acids to release citric acid and calcium salts
Conditions to Avoid: Excessive humidity, strong acids or alkalis, elevated temperatures
Incompatible Materials: Strong oxidizers, concentrated acids
Hazardous Decomposition Products: At high temperatures, releases CO2 and calcium oxide
Acute Toxicity: Low oral toxicity; high doses can cause gastrointestinal upset (nausea, diarrhea)
Chronic Effects: No known chronic health effects under normal use
Inhalation Risk: High dust levels can cause mild respiratory irritation
Skin/Eye Contact: May cause mild local irritation with repeated exposure
Carcinogenicity: No evidence, not listed by NTP, IARC, or OSHA
Sensitization: No significant data, rare irritation possible
Ecotoxicity: Low toxicity to aquatic and terrestrial life at concentrations typical of environmental exposure
Persistence and Degradability: Citrate ion is biodegradable; calcium component binds to soil
Bioaccumulative Potential: Does not bioaccumulate
Mobility in Soil: Limited, forms insoluble calcium compounds, reduces environmental migration
Other Effects: Large discharges can impact water hardness and possibly influence aquatic species
Waste Handling: Collect unused material in containers, dispose of through licensed facility
Product Disposal: Non-hazardous waste under most regulations; if unsure, treat as chemical waste
Contaminated Packaging: Wash before re-use or disposal, follow local regulations
Environmental Precautions: Do not allow significant amounts to reach groundwater or watercourses
UN Number: Not regulated for transport
Transport Hazard Class: None, not a dangerous good
Packing Group: Not required
Proper Shipping Name: Calcium Citrate
Special Precautions: Protect from moisture and physical damage during transport
Regulatory Information: Ensure labeling and documentation per carrier requirements
Safety Legislation: Meets requirements for food-grade or pharmaceutical-grade additives, as regulated by authorities like FDA, EFSA
Classification: Not considered hazardous under GHS, OSHA, WHMIS
Labeling: Not regulated as a hazardous chemical for workplace or transport
Inventory Listings: Listed in TSCA, EINECS, DSL, AICS, and other global chemical inventories
Other Standards: Specifications outlined by USP, FCC, or similar pharmacopoeial standards apply for finished product
