Product Name: Choline Dihydrogen Citrate
Synonyms: Choline citrate, Choline hydrogen citrate
CAS Number: 77-91-8 (choline), 77-92-9 (citric acid component)
EC Number: 201-053-9
Recommended Use: Laboratory chemicals, feed additives, nutritional supplement
Manufacturer: Contact relevant supplier or chemical manufacturer for up-to-date emergency contact information and local representative details
Emergency Phone: Refer to national poison control or local chemical emergency hotline
GHS Classification: Not classified as hazardous according to GHS
Main Hazards: May cause irritation to eyes, skin, and respiratory tract on contact or inhalation; ingestion can produce gastrointestinal discomfort
Pictogram: No applicable pictograms based on current classification
Signal Word: No signal word required under GHS
Hazard Statements: May cause mild skin/eye irritation; prolonged or repeated exposure may cause allergic reactions in sensitive individuals
Precautionary Statements: Avoid contact with skin and eyes; wash thoroughly after handling; maintain adequate ventilation in work area
Chemical Name: Choline Dihydrogen Citrate
Formula: C8H19NO7
Component 1: Choline - ~50%
Component 2: Citrate Ion (from citric acid) - ~50%
Purity: Pure grade, typically >98%
Impurities: Water of crystallization possible, trace residuals from manufacturing (none identified as significant hazard)
Inhalation: Move affected person to fresh air; seek medical attention if respiratory symptoms appear or persist
Skin Contact: Remove contaminated clothing; rinse exposed skin with plenty of water and soap; obtain medical advice if irritation occurs
Eye Contact: Rinse eyes immediately with clean water for several minutes, lifting upper and lower eyelids occasionally; consult a physician if discomfort continues
Ingestion: Rinse mouth thoroughly with water; do not induce vomiting unless recommended by healthcare professional; seek immediate medical attention if discomfort develops
Special Notes: No specific antidote; treat symptoms as needed
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam
Unsuitable Media: Do not apply direct water jet onto burning product; risk of splattering
Thermal Decomposition: May produce oxides of carbon, nitrogen oxides, and potentially irritating fumes
Special Protective Equipment for Firefighters: Standard firefighting gear, self-contained breathing apparatus
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, possible irritating organic vapors
Explosion Data: Not explosive under normal conditions; dust may form explosive mixtures in air at high concentrations
Personal Precautions: Evacuate unnecessary personnel from spill area; avoid contact with skin, eyes, or inhalation of dust
Protective Equipment: Use gloves, goggles, and suitable protective clothing; use a dust mask or respirator in poorly ventilated areas
Environmental Precautions: Prevent product from entering drains, watercourses, or soil in large quantities
Spill Clean-Up Methods: Sweep up spillage using non-sparking tools and place in closed containers for disposal; clean area with water after material removal
Handling: Work in a well-ventilated environment; avoid dust formation; wear appropriate protective equipment to prevent skin and eye contact; handle in accordance with good industrial hygiene and safety practice
Storage: Store in a cool, dry, and well-ventilated area away from incompatible materials such as strong oxidizers; keep container tightly closed when not in use; prevent moisture ingress; store away from food and beverages
Special Precautions: Use only stipulated containers; ensure all handling areas are clearly labeled and equipped to contain spillages
Occupational Exposure Limits: No exposure limits established by OSHA, ACGIH, or EU authorities at time of writing
Engineering Controls: Use local exhaust ventilation to minimize exposure; provide eyewash stations and safety showers
Respiratory Protection: Approved dust mask or respirator for significant dust, especially in unventilated spaces
Skin Protection: Nitrile or neoprene chemical-resistant gloves; lab coat or protective clothing
Eye Protection: Chemical safety goggles or glasses with side shields
Hygiene Measures: Wash hands and exposed skin after handling, before breaks, and at end of workday
Appearance: White to off-white crystalline powder
Odor: Mild, characteristic odor
pH: Approximately 3 - 4 (1% solution in water)
Melting Point: No specific data; decomposes at elevated temperatures
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Soluble in water; insoluble in most organic solvents
Flash Point: Not determined; presumed non-flammable
Relative Density: Around 1.4 g/cm³ (estimated)
Vapor Pressure: Negligible at ambient conditions
Auto-ignition Temperature: No relevant data; not expected to self-ignite
Partition Coefficient (log Kow): Not determined
Chemical Stability: Stable at room temperature and standard handling conditions
Reactivity: No hazardous reactions under normal use; incompatible with strong oxidizing agents
Conditions to Avoid: Excessive heat, moisture, open flames, or sources of ignition
Hazardous Decomposition Products: Forms oxides of carbon, nitrogen, and minor amounts of irritating or toxic gases when heated to decomposition
Polymerization: Does not undergo dangerous polymerization reactions
Likely Routes of Exposure: Inhalation, skin or eye contact, ingestion
Acute Toxicity: Expected to be of low toxicity to humans; LD50 (oral, rat) estimated >2,000 mg/kg based on similar choline salts
Skin Contact: May cause mild irritation after prolonged or repeated exposure
Eye Contact: May cause temporary discomfort, redness, or watering
Chronic Effects: No clear data on chronic toxicity; repeated large doses can cause digestive upset
Sensitization: Not classified as sensitizer; rare allergic responses in predisposed individuals are possible
Carcinogenicity, Mutagenicity, Reproductive Effects: No data indicating risk based on available scientific literature
Ecotoxicity: Not expected to be toxic to aquatic life at typical concentrations; readily degrades to naturally occurring compounds
Persistence and Degradability: Easily biodegradable in soil and water
Bioaccumulation: No potential for bioaccumulation due to high solubility and rapid degradation
Mobility in Soil: High; likely to leach if released, but environmental impact is minimal
Other Adverse Effects: Not known; avoid large releases to prevent possible eutrophication in water bodies
Waste Disposal Methods: Dispose of according to local, regional, and national legislation; incineration or landfill if approved facility available
Empty Container Precautions: Rinse thoroughly to remove residues; recycle or dispose according to established guidelines
Additional Notes: Do not discharge product into the environment; use appropriate waste management providers for industrial quantities
UN Number: Not regulated for transport by road, rail, sea, or air
Proper Shipping Name: Choline Dihydrogen Citrate
Hazard Class: Not classified as hazardous by transport regulations
Packing Group: Not applicable
Transport Labeling: No special labeling requirements
Special Precautions: Avoid mechanical damage to packaging; protect from moisture during transit
Inventory Status: Listed in major chemical inventories (TSCA, EINECS, DSL, etc.)
Labeling Requirements: Follows national and local hazard communication rules
OSHA Hazards: Not specifically regulated
SARA Title III: Not listed under hazardous substances
Other Regulations: Complies with REACH and related European chemical safety directives; not subject to special restrictions as of data sheet preparation
Workplace Classification: Maintain updated record as part of risk analysis and chemical register as required by safety management systems
