CITROFOL BII: Behind the Scenes of a Modern Plasticizer

Historical Development

Today’s market buzzes with talk about eco-friendly chemicals, but few pause to look back. The journey of citrate esters like CITROFOL BII traces to the demand for safer, less toxic plasticizers. Early solutions leaned heavily on phthalates. Over decades, as research flagged the health risks from phthalates, manufacturers hunted alternatives. By the mid-20th century, citric acid-based esters drew attention. Chemists focused on tributyl O-acetylcitrate, commonly known as CITROFOL BII, for its digestibility, low toxicity, and origins in renewable resources. Years of iteration and small lab victories turned into broader commercial production. The regulatory environment kept tightening and consumer awareness mushroomed, so the study of such esters only deepened. As governments started linking certain chemicals to developmental harm in children and environmental contamination, industry players treating public safety as an afterthought found themselves scrambling. The story of CITROFOL BII is a case study in changing priorities—health concerns and regulatory actions nudging science in new directions.

Product Overview

CITROFOL BII, or tributyl O-acetylcitrate, fills a crucial gap for makers of soft plastics. This compound isn’t meant for chemistry textbooks only; it finds its way into food packaging films, toys, cosmetics, and even medical devices. Its structure, derived from citric acid mixed with butanol and acetic anhydride, brings about a flexibility in finished products that’s hard to match. Unlike phthalate-laden alternatives, CITROFOL BII bundles a balance between performance and safety. It holds up against regulatory demands for biocompatibility, which means its journey from lab to lunchbox involves fewer hurdles. Companies that once faced tough choices now see it as a reliable way to sidestep older controversies without compromising on material quality.

Physical & Chemical Properties

Looking at CITROFOL BII under a microscope or running it through a chemical analyzer, certain features come up every time. It’s clear and colorless with a faint odor, resembling many plasticizers. The real magic comes from its molecular architecture: three butyl groups and an acetyl cap bound to a citric backbone. This structure gives a boiling point well above 300°C, and a flashpoint over 200°C. It shows low volatility, so it won’t just evaporate off into thin air. Its compatibility with polymers, especially PVC, means it doesn’t just sit on the surface—it integrates right into the mix. Because it resists hydrolysis under normal manufacturing conditions, users can count on stable shelf life. It blends smoothly with plastic resins and doesn’t leach as easily, a property scientists have exploited to meet tighter migration limits in food contact materials.

Technical Specifications & Labeling

Industry folks specifying CITROFOL BII expect certain benchmarks: purity typically above 99%, water content kept under 0.2%, acid value below 0.2 mg KOH/g, and standardized refractive index. A quick glance at a spec sheet turns up density at around 1.05 g/cm³, viscosity in a reasonable range for high-speed extrusion, and all the usual certifications—REACH, FDA, and European Food Safety Authority approvals for intended uses. Packaging labels warn about long-term storage above 40°C and the usual advice for chemical products, but hazards sit low compared to many plasticizers. Only those with specific intolerances or allergies need to raise concerns, which simplifies things for everyone across the supply chain.

Preparation Method

Making CITROFOL BII doesn’t require state secrets; the process depends on accessible feedstocks and standard gear. Operators start with citric acid, reacting it first with butanol in the presence of a strong acid catalyst to make tributyl citrate. The next step acetylates the free hydroxyl group using acetic anhydride, producing tributyl O-acetylcitrate. This two-step process involves distillation and purification rounds to drive off residual solvents and unreacted materials. Scaling from lab bench to industrial reactor takes careful tweaking of timing, temperature, and mixing so the product avoids unwanted side reactions. Chemists keep an eye out for color changes—yellow means impurities are creeping in. Consistency batch to batch propels the trust buyers put in the product, and I’ve seen operations build an entire reputation on controlling these subtleties.

Chemical Reactions & Modifications

The core chemistry hinges on esterification and acetylation. These reactions play out smoothly as long as feeds stay pure and the acid catalyst remains in range. If someone down the line seeks to tailor the physical behavior, substitutions on the alkyl groups or slight changes in the acetylation step can tweak migration rates and plasticizer performance. The reactivity of the citrate core also opens doors for chemical modification, making derivatives with added properties—maybe UV resistance or special dye uptake. While the technical crowd can get lost in the weeds of side reactions, most commercial users stick with standard CITROFOL BII for reliability and proven regulatory acceptance.

Synonyms & Product Names

A trip through chemical catalogs reveals a scatter of aliases: tributyl O-acetylcitrate, acetyltri-n-butyl citrate, and the E number E1518 in the context of food additives. European Safety agencies or the FDA may reference it on labels as acetyl tributyl citrate. Major suppliers adopt their own branding: CITROFOL BII by Jungbunzlauer, ATEC by Vertellus, sometimes ATBC shows up though it may cover broader grades. These synonyms can trip up newcomers, so reading the fine print on datasheets pays off.

Safety & Operational Standards

Transitioning away from phthalates, industry still faces scrutiny about long-term exposure. Various studies have probed CITROFOL BII’s health impacts; so far, no evidence points to hormone disruption or carcinogenicity. It’s listed for use in food contact applications within EU and US, subject to migration limits drastically lower than alternatives from the old playbook. Operators don’t need inhalation masks for handling at ambient temperatures, though gloves and glasses stay standard in production lines to manage any accidental splashes. Storage follows usual rules for organic liquids: ventilated, temperature-controlled, sealed tight. Over the years, safety documentation piled up, and regular reviews keep guidelines in step with changing regulations and new research findings.

Application Area

Step into a hospital and there’s a decent chance that IV tubing, blood bags, or soft syringes use CITROFOL BII as a plasticizer. Food packaging—cling films and squeeze bottles—demand plasticizers that won’t leach toxins or taint taste. Regulatory bodies scrutinizing baby toys or toothbrush handles demand non-toxic, stable compounds. Even nail polish and some hair styling products pull on CITROFOL BII’s solvent and stabilizing roles. Its ability to keep materials soft, flexible, and durable—without raising the toxicological red flags that follow many competitors—has expanded its reach beyond niches. As awareness about microplastics and chemical safety grows, more manufacturers switch away from legacy solutions toward options like CITROFOL BII, prompted by consumer advocacy or the rising tide of chemical restrictions.

Research & Development

The lively landscape of green chemistry doesn’t sit still, and those working with CITROFOL BII keep pushing for more sustainable feedstocks and cleaner production. Research teams delve into optimizing catalyst schemes or designing reactors to minimize waste. Some target even higher purity or look into enzyme-assisted synthesis for energy savings. Partnerships between academic groups and chemical suppliers have produced a handful of new citrate-based molecules, but most studies circle back to how CITROFOL BII interacts with modern bioplastics, or how migrating even less from containers to contents might be engineered. The challenge comes down to balancing costs, process complexity, and the strict watch of regulators. As the bioeconomy advances, production facilities get retooled and supply chain audits deepen, spinning new questions about traceability and residual contaminants into the research cycle.

Toxicity Research

With headlines flagging chemicals that disrupt hormones or linger for decades, toxicologists have kicked the tires on CITROFOL BII from every angle. Most published data shows it breaks down in soil and water, bringing biodegradable credentials that matter for environmental regulators. Animal testing has yet to turn up major organ toxicity or cancer signals at exposure levels far beyond what a consumer might encounter. That said, researchers continue sniffing around for subtler links—chronic effects, allergenic responses, or bioaccumulation in aquatic organisms. European authorities set strict migration thresholds: less than 1 mg/kg food for most packaging uses. Compliance monitoring pulls random samples, and so far, results have largely reassured watchdogs. Having followed plastics debates for years, I find the shift in focus—away from short-term toxicity to environmental persistence and cumulative impacts—reflects a smarter approach that puts safety in real-world contexts, not just lab mice.

Future Prospects

Looking ahead, the demand for safe and sustainable plasticizers won’t taper. Regulatory changes in the US, EU, and Asia spark fresh innovation each year. CITROFOL BII’s success so far comes from straddling the line: deliver technical performance without landing on chemical watch lists. As consumers flex more power around “clean label” packaging and medical supply buyers push for tested safety records, the competitive runway for CITROFOL BII extends. Next-gen bioplastics bring new compatibility puzzles, so research on “greener” derivatives of citrate esters marches on. The adoption of renewable energy at chemical plants and pressure to lower overall carbon footprints also drive process changes. Markets from food, medical, and consumer goods increasingly cross-pollinate, looking for reliable plasticizers that won’t trigger public backlash. Don’t expect smooth sailing—price swings, feedstock shortages, or new claims about chemical residue could still jolt things—but the track record built by CITROFOL BII sets a high bar for the next wave of innovation.




What is CITROFOL BII used for?

What’s In a Name?

CITROFOL BII doesn’t pop up in day-to-day conversation. Even lifelong chemistry buffs might pause. But take a look around, and this substance shows up more often than most realize. It’s a plasticizer, based on citric acid, and it goes straight into stuff we handle all the time: toys, food packaging, cosmetics. What drew folks to CITROFOL BII in the first place? Stress around the health impact of old-school plasticizers like phthalates. These older ingredients have made the news for all the wrong reasons, mainly over links to hormone disruption and environmental messes.

Shaping Plastics Without Phthalates

Think about kids’ rubber ducks or the soft vinyl on those food pouches in your lunch. The rubbery, flexible feel doesn’t come for free. Blame—or thank—plasticizers for that. For decades, manufacturers stuck with phthalates because they worked. Trouble is, phthalates also raised public health risks, especially in things that touch food or get chewed by babies. CITROFOL BII changed the chessboard: it does the work of making plastic soft and bendy, but uses ingredients that come from natural origins, so there’s less worry about toxic run-off or unwanted chemicals building up in living bodies.

Safer Choices for Families

It doesn’t take long at a department store to see the impact. Pull a new chew toy off the shelf, scan the label, and you may spot “phthalate-free” right up front. CITROFOL BII plays a part behind those labels. Regulations in the US and Europe push manufacturers to dump dodgy ingredients from items that touch mouths, skin, or food. By switching over to citric-based plasticizers, companies signal to parents that their products steer clear of the risks tied to old plastic chemistry. Consumer trust matters, and it grows faster when families feel confident there’s no hidden tradeoff between safety and durability.

Cosmetics and Personal Care

It’s not just about plastics. Creams, lotions, nail polishes, and hair products also need a way to keep smooth and stable. A good plasticizer keeps cosmetics from turning brittle or sticky. Here, CITROFOL BII turns up because it’s gentle and doesn’t leave harsh residues. Some folks have skin that acts up at the mention of harsh chemicals, so ingredients like this pull double duty—easing the worries of sensitive users while helping companies meet tighter ingredient rules. Beauty shouldn’t come with regret or a rash.

Food Safety and Packaging Concerns

Most people don’t think twice about the lining inside a takeout container or the wrap around a slice of cheese. That lining can come from plastics needing just the right flex. CITROFOL BII gets the nod from food safety agencies for use in packaging films that won’t leach harmful chemicals. Knowing this, avoiding contamination feels a bit more possible. Even as food wraps and containers get tossed out or recycled, there’s less reason to worry about the stuff left behind in soil or water. It isn’t magic, but it does lighten the load on our health and on the planet.

Looking Ahead: Better Plastics, Fewer Worries

There’s no simple switch to a plastic-free world, so making plastics safer makes sense. CITROFOL BII reminds makers that you can craft goods with flexibility and still listen to the science. The biggest impact comes when these changes scale up—imagine every hospital IV bag, every picnic fork, every baby rattle trading out risky additives for safer alternatives. It’s not just about satisfying regulations. It’s about respect for the people down the line—kids, workers, folks at home—who count on products not making them sick.

Is CITROFOL BII a safe plasticizer?

Looking at Plasticizer Choices in Everyday Products

Plastic surrounds everyday life — tucked into food packaging, medical supplies, electronics, even the toys tossed around by kids. The kind of plasticizer mixed into those products makes a difference, not just for how bendable the material feels, but for health and environmental safety. CITROFOL BII, known in chemistry as triisobutyl citrate, has popped up as an alternative to old-school plasticizers like phthalates, which lost favor over toxicity concerns.

CITROFOL BII vs. Phthalates — Safety Makes the Difference

A few years back, stories hit the news warning about phthalates leaching from plastics. These chemicals, once found in just about every soft plastic, linked to hormone disruption, developmental problems, and increased risks for asthma and allergies in children. Governments started blocking phthalates in baby products, food packaging, and medical tools. Plant-based options began to fill the gap.

CITROFOL BII comes from citric acid. You see citric acid listed on food labels all the time, squeezed from citrus fruits and safely eaten for generations. Manufacturers prize CITROFOL BII because, unlike those phthalates, it's less likely to carry over major toxicological baggage. Lab tests give it a good safety profile — it usually doesn’t mess with hormone systems nor trigger hypersensitivity in most people. In Europe, the food industry gave it approval as a food additive (E1505). When regulators sign off on making it part of products that contact food, that lends some trust.

Medical, Food, and Personal Use — Looking Further Into Safety

The medical world uses plasticizers, too, especially in tubing, IV bags, and flexible containers. CITROFOL BII has earned its slot in these fields. Research out of Europe and the U.S. shows low migration rates — meaning, less chance to leach out into fluids or the body under normal use. That’s a big deal, especially when compared to DEHP and similar phthalates, which don’t stay put and show up in blood samples of hospitalized patients.

A big question: does switching to CITROFOL BII bring new problems to the table? Studies so far show it's less likely to bioaccumulate, and the body breaks it down fast, passing it out through urine as simple metabolites. So far, it hasn’t shown chronic toxicity, reproductive issues, or cancer risk in major animal studies. Still, it hasn’t run through every possible scenario. No one has rolled out multi-decade studies in humans. Babies, pregnant women, and those with weakened immune systems stay especially vulnerable, so it pays to keep tabs on new data as it rolls out.

Environmental Impact and the Path Ahead

Relying more on plant-derived plasticizers could help answer some of the old headaches that came with fossil fuel-based chemistry. CITROFOL BII pops up as biodegradable, not stacking up in waterways or food chains in the same way as many older chemicals. That’s good for wildlife, and good for people worried about what flushes out of plastics.

A product’s safety story stretches beyond its laboratory tests. Oversight from agencies like the FDA, EU’s EFSA, and national health ministries helps weed out bad actors. At the same time, companies carry a share of the responsibility — sticking with tested, high-purity versions, and pushing for more transparency. Parents, patients, and anybody shopping for food want clear labeling, especially if they’re shopping for little ones or nursing health issues.

Thinking It Through

CITROFOL BII represents progress away from the worst plasticizer offenders. Most research so far backs its safety for food and medical use, with less risk than phthalates. There’s room left to double down on long-term studies, monitor real-world exposure, and keep the spotlight on new ingredients angled as “green” solutions. Progress means more than swapping one chemical for another — it means keeping health and the environment top of mind, every step of the way.

What are the main chemical properties of CITROFOL BII?

Understanding CITROFOL BII

CITROFOL BII pops up in many places, from children’s toys to food packaging. This compound goes by its technical name, triisobutyl citrate. It belongs to the family of citrate esters, which step in as alternatives to phthalate plasticizers. Whenever I run into a plastic product claim that says “phthalate-free,” my eyes head straight to what’s replacing them. Triisobutyl citrate usually ranks high on the list, and there's good reason for it.

Chemical Traits that Set CITROFOL BII Apart

One of the main things about CITROFOL BII is how it handles water and other chemicals. It doesn’t dissolve well in water. That keeps it from leaching much out of plastics if they get wet. This matters for items like bath toys or food-contact wraps. On the flip side, it mixes much better with compounds found in plastics and rubber, improving flexibility without making things greasy or sticky. I’ve watched manufacturers favor it for this, especially with products that toddlers chew on or gnaw at for hours.

Acidity and reactivity are low. Once in a polymer, CITROFOL BII tends to settle down and stay put. Chemical reactions with common household cleaners don’t usually break it down. High heat doesn’t faze it; plastic containers and wraps don’t ooze or change at the usual temperatures found in kitchens or playrooms. For those of us concerned about endocrine disruptors or toxic residues, this stability means fewer worries. There’s no big cloud of vapor, no sharp smell, and no surprise side effects.

A big part of what makes CITROFOL BII handy is its ability to blend in without stealing the show. The compound is clear, nearly odorless, and practically invisible once inside plastic. These properties mean less risk of allergens and fewer complaints about smell or taste invading food. European regulators look for this kind of clean profile, and CITROFOL BII fits the bill.

Potential Concerns and What Can Help

Of course, questions come up about any plasticizer, including CITROFOL BII. Some folks worry about breakdown products over time. Triisobutyl citrate does eventually break down into citric acid and a handful of other organic acids if left for years. Studies suggest these aren’t harmful in small amounts, but long-term use in high-heat settings could call for more investigating. I keep thinking—will next year’s research find issues we missed? Still, compared to phthalates, which have well-documented health risks, CITROFOL BII so far stands as a safer pick.

If there’s a way forward, it starts with more transparency. Manufacturers sometimes stay quiet about what’s inside plastics, letting rumors fill the gap. Companies who share their formulas build trust and cut down on worry. Regulators also look at how plasticizers act after disposal—especially since microplastics have become such big news. Switching to plant-based sources for citrate esters can shrink the environmental footprint, too.

Looking for Solutions

People want safe materials touching their food and bodies. CITROFOL BII checks important boxes when used right, but nothing replaces good research and strict oversight. If research finds unexpected problems down the road, chemistry gives us new options. Bio-based additives, further testing in real-world settings, and honest labeling all help people make smarter choices. For now, CITROFOL BII delivers performance with a safety record that has folks in labs and households breathing a little easier.

In which industries is CITROFOL BII typically applied?

The Push for Safer Plasticizers

If you’ve ever worried about the chemicals that go into everyday plastic products, you’re not alone. CITROFOL BII, a citrate-based plasticizer, stands out because it steers away from some of the health questions tied to old-school phthalates. People in the plastics world look for safer, less toxic alternatives that still get the job done—especially for stuff that touches your food or skin. That’s where CITROFOL BII makes its mark.

Food Packaging Gets a Healthier Boost

Walk through any grocery store and you’ll notice a sea of plastic—cling films, trays, and takeout containers. All these bits of plastic need some flexibility. CITROFOL BII finds a home here, lending flexibility without raising red flags about chemicals leaching into what we eat. Regulatory folks have given it a nod thanks to its lower toxicity. The safety standards are especially strict for food packaging, so every ingredient needs to be above board. Knowing that what wraps your sandwich isn’t laced with questionable additives is a relief, both for big manufacturers and everyday shoppers.

Toys and Baby Products Matter Most

Think of kids grabbing a chewable giraffe or a squishy ball—anything meant for play, but often headed straight for the mouth. For years, regulators flagged certain plasticizers used in toys. Parents pushed back against anything that might put their kids in harm’s way. CITROFOL BII offers a softer touch for companies building rattles, teething rings, and soft vinyl dolls. Painstaking work goes into picking materials for these products, and confidence in the ingredients spills over to trust in the toy aisle. Safety in children’s goods shouldn’t be a gamble, and safer plasticizers make a real impact.

Health and Beauty in Flexible Packaging

Products like flexible tubes for lotions and shampoos or films for bath salts have their own demands. The stuff inside should be easy to squeeze out, and nobody wants packaging that cracks or feels stiff. This kind of application draws on plasticizers that can handle constant flexing without breaking down or getting brittle. CITROFOL BII handles this job, especially where the manufacturer wants to avoid potential allergens or irritants. Formulations for products used close to skin or hair can’t compromise on safety, not just because rules say so, but because consumers are reading labels more closely than ever.

Medical Sector Stakes: Safety Comes First

Hospitals and clinics wrap and store everything from bandages to intravenous bags in plastic. For these, flexibility without contamination risks is priority number one. While nothing is perfect, CITROFOL BII has made progress as a plasticizer for medical tubing, blood bags and glove manufacturing. Even small chemical differences can mean a lot when it comes to something as sensitive as medical equipment. Having an option that passes strict testing and doesn’t come with legacy problems earns it trust in this high-stakes world.

What Could Come Next?

More industries seek out this kind of solution. Electronics packaging, interior car trims, and even art supplies begin shifting to plasticizers less likely to run into future health bans or restrictions. The drive for change starts from real-world needs: folks want materials that last, remain safe, and perform as promised. As I see it, supporting innovation in safer plasticizers opens doors for healthier homes, confident consumers, and a materials industry that finally moves past the old trade-offs.

Is CITROFOL BII biodegradable or environmentally friendly?

Breaking Down What's in the Bottle

Every time a new ingredient gets tossed around with buzzwords like “biodegradable” or “eco-friendly,” my skepticism clock starts ticking. CITROFOL BII, a plasticizer based on citric acid esters, has been popping up on more manufacturer spec sheets, usually with a long list of green claims. On the surface, anything that swaps oil-based chemicals with something that comes from fruits seems like a step in the right direction. But after years of watching greenwashing roll through the chemical industry, digging deeper always feels necessary.

Where CITROFOL BII Comes From

Markets describe CITROFOL BII as “derived from renewable resources”—specifically, citric acid sourced mostly from sugar beets or corn. Instead of some acrylic monomer with a tongue-twister name, this stuff gets made by esterifying citric acid with butanol. That sounds more wholesome compared to traditional plasticizers like phthalates, which keep making headlines for showing up in everything from toys to river sediment. But just because something is plant-based doesn’t mean it disappears back into the soil without a trace.

Biodegradability: Fact or Fancy?

Looking at the data, CITROFOL BII gets a thumbs-up for being “readily biodegradable” under the OECD 301 tests. Lab results show it degrades fast in the presence of microbes. There’s nothing magic about it—bacteria and fungi see this molecule, find it pretty easy to chew up, and convert it to carbon dioxide and water without too much hassle. That's a win, considering phthalates and some other plasticizers linger for years. Still, test tubes tell only part of the story. Out on the street, in a landfill, or washing down the drain, not every environment works like a controlled lab bench. I’ve seen biodegradable materials hang around because conditions didn’t line up.

Environmental Impact—Beyond the Numbers

I’ve worked with enough green chemicals to know each one comes with trade-offs. Processing CITROFOL BII needs a steady flow of butanol—which doesn’t always come from renewable sources. Though the product reduces reliance on fossil fuels and limits toxic residues, it’s not immune to supply chain quirks. Growing and fermenting the feedstock burns energy and demands water, leaving a footprint that can’t get swept under the carpet. The agricultural side brings up questions about land use, fertilizer run-off, and monoculture farming, the usual suspects in modern agri-business.

What Makes Something “Environmentally Friendly”?

Labels like “environmentally friendly” float around way too loosely. For most buyers, just knowing a chemical breaks down in lab tests isn’t the whole story. I’ve watched companies swap to bio-based plasticizers only to find leaks elsewhere, like higher costs or harder sourcing. If waste streams aren’t managed right, fragments can still build up before breaking down, and not all downstream users—think emerging countries—have the waste management or composting infrastructure to manage these new bioplastics. Microplastic pollution isn’t solved by a molecule that breaks down if nobody collects and processes the waste properly.

Where CITROFOL BII Fits In and How to Do Better

CITROFOL BII has a lot going for it and works as a safer replacement where reducing toxicity matters—like food-contact packaging, films, or coatings. But real progress comes when the conversation doesn’t stop at the factory door. Transparency about sourcing, life cycle assessment, and third-party verification of green claims all need to move up the priority list. Investing in waste collection and processing infrastructure, and focusing on real-world degradability, makes more difference than slapping “eco-friendly” on a bottle. If companies tell the whole story, users get the tools to make better choices—not just for the lab, but for the world outside it.

CITROFOL BII
Names
Preferred IUPAC name bis(2-butoxyethyl) benzene-1,2-dicarboxylate
Other names Tributyl O-acetylcitrate
Acetyl Tributyl Citrate
ATBC
Pronunciation /ˈsɪtrəˌfɒl biː aɪ aɪ/
Identifiers
CAS Number 3066-91-1
3D model (JSmol) `3D structure;C(C(CO)OC(=O)C(C)(C)C)(CO)OC(=O)C(C)(C)C`
Beilstein Reference 1722765
ChEBI CHEBI:85191
ChEMBL CHEMBL2034360
ChemSpider 91371
DrugBank DB11095
ECHA InfoCard The ECHA InfoCard of product 'CITROFOL BII' is: **03b64a39-245c-4be9-b29a-b0cb0e91bd5b**
EC Number 265-124-0
Gmelin Reference 5976
KEGG C18617
MeSH Diethylhexyl Isobutyrate
PubChem CID 8778
RTECS number OJ6300000
UNII YO1UK4S6SI
UN number UN2811
CompTox Dashboard (EPA) CompTox Dashboard (EPA) of product 'CITROFOL BII' is "DTXSID20112
Properties
Chemical formula C13H24O4
Molar mass 446.56 g/mol
Appearance Clear, colourless liquid
Odor Faint odor
Density 1.045 g/cm3
Solubility in water insoluble
log P 2.12
Vapor pressure < 0.01 hPa (20°C)
Acidity (pKa) “Acidity (pKa): 3.18”
Basicity (pKb) 13.7
Magnetic susceptibility (χ) Diamagnetic
Refractive index (nD) 1.445 - 1.449
Viscosity 28 mPa·s
Dipole moment 3.57 D
Thermochemistry
Std molar entropy (S⦵298) 503.7 J·mol⁻¹·K⁻¹
Std enthalpy of combustion (ΔcH⦵298) -7068 kJ/mol
Pharmacology
ATC code A07EC02
Hazards
Main hazards May cause respiratory irritation.
GHS labelling GHS07
Pictograms GHS07
Signal word Warning
Precautionary statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
NFPA 704 (fire diamond) 1-1-0
Flash point 185°C
Autoignition temperature 410 °C
Explosive limits Lower explosion limit (LEL): 0.9% (V); Upper explosion limit (UEL): 6.4% (V)
Lethal dose or concentration LD50/oral/rat = 14,300 mg/kg
LD50 (median dose) > 15,800 mg/kg (rat, oral)
PEL (Permissible) PEL (Permissible Exposure Limit) for CITROFOL BII: Not established
REL (Recommended) 16 mg/kg bw
IDLH (Immediate danger) Not established
Related compounds
Related compounds CITROFOL AI
CITROFOL AII
CITROFOL BI
CITROFOL CA