Product Name: Clomiphene Citrate
Chemical Formula: C26H28ClNO • C6H8O7
Synonyms: Clomid, Serophene
CAS Number: 50-41-9
Molecular Weight: 598.08 g/mol
Supplier: Contact local distributor or manufacturer
Recommended Use: Pharmaceutical ingredient, research purposes
Restrictions on Use: Prescription medication, not intended for unauthorized handling
Classification: Harmful if swallowed, suspected of damaging fertility, eye irritation
GHS Label Elements: Exclamation mark, Health hazard symbol
Signal Word: Warning
Hazard Statements: May cause allergic skin reactions, suspected reproductive toxicity, may cause mild respiratory irritation, risk of eye and mucous membrane irritation
Precautionary Statements: Wear protective gloves and clothing, avoid inhalation and contact with skin or eyes, wash thoroughly after handling, keep away from food and drink
Chemical Name: Clomiphene Citrate
Concentration: ≥99% (active compound in pure form)
Relevant Impurities: Trace manufacturing impurities, typically pharmaceutical grade
Other Information: Contains no additional hazardous substances beyond trace solvents and water utilized in synthesis or crystallization
Inhalation: Move person to fresh air, seek medical attention if symptoms develop, provide oxygen support if breathing is affected
Skin Contact: Remove contaminated clothing, rinse skin with soap and plenty of water for at least 15 minutes, contact medical services for persistent discomfort
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, seek immediate medical attention
Ingestion: Rinse mouth with water, seek immediate medical advice, do not induce vomiting unless instructed by medical personnel, monitor for adverse symptoms
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, alcohol-resistant foam
Specific Hazards from Fire: Toxic fumes of hydrogen chloride, nitrogen oxides, carbon oxides may form upon combustion
Special Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear when entering area of active fire
Advice for Firefighters: Move containers from fire area if it can be done safely, keep unaffected containers cool with water spray, contain run-off to prevent environmental contamination
Personal Precautions: Wear lab coat, protective gloves, goggles, dust mask or respirator
Spill Response: Avoid inhalation, ventilate area, clean up dusts and spills using approved HEPA filter vacuum or wet methods, do not allow material to enter drains
Environmental Precautions: Prevent discharge into soil, water sources, or sewage systems
Containment and Cleanup: Sweep or scoop material into suitable labeled containers for recycling or disposal, wash spill site after material pickup is complete
Handling Precautions: Avoid contact with skin, eyes, and clothing; minimize dust generation; handle under local exhaust ventilation; wash hands thoroughly after handling
Hygiene Measures: Do not eat, drink, or smoke during use; decontaminate protective clothing before reuse; implement regular workplace cleaning schedules
Storage Conditions: Store in a tightly closed container, in a cool, dry, well-ventilated area, away from sources of ignition, incompatible materials like strong oxidizers or acids
Special Storage Needs: Protect from light and moisture, keep container tightly sealed when not in use
Exposure Limit Values: No established occupational exposure limits, minimize exposure using best practices for pharmaceutical handling
Engineering Controls: Use enclosed processes and local exhaust ventilation, employ high-efficiency particulate filters on laboratory hoods
Personal Protection: Nitrile or neoprene gloves, chemical splash goggles, laboratory coat or gown, NIOSH-approved respirator for dust generation
Environmental Exposure Controls: Prevent release to environment, implement site-specific waste control practices
Appearance: White to off-white crystalline powder
Odor: Odorless or slight characteristic odor
Odor Threshold: Not applicable
pH: Slightly acidic to neutral when dissolved
Melting Point: 116-118°C
Boiling Point: Not readily volatile, decomposition occurs before boiling
Flash Point: Not available
Flammability: Not classified as a flammable solid
Vapor Pressure: Negligible at room temperature
Solubility: Sparingly soluble in water, soluble in ethanol, methanol, chloroform
Partition Coefficient (log Kow): Expected to be moderately lipophilic
Auto Ignition Temperature: Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable (solid
Chemical Stability: Stable under ordinary conditions of storage and handling
Reactivity: No hazardous reactions expected under normal conditions
Incompatibilities: Strong oxidizers, strong acids
Hazardous Decomposition Products: Nitrogen oxides, hydrogen chloride, carbon oxides during thermal decomposition
Polymerization: Will not occur
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Low to moderate oral toxicity (based on data in lab animals)
Chronic Effects: May cause reproductive effects, possible liver dysfunction with repeated exposure, risk increases with high or sustained dosing
Symptoms of Overexposure: Headache, dizziness, flushing, abdominal discomfort, visual disturbances, rash
Carcinogenicity: Not listed as a known human carcinogen by IARC, NTP, or OSHA
Mutagenicity: No significant evidence in standard assay systems
Reproductive Effects: Suspected risk to fertility and fetal development
Sensitization: May provoke allergic skin responses in susceptible individuals
Toxicity to Aquatic Life: Data limited, may cause harmful effects to aquatic organisms at high concentrations
Persistence and Degradability: Not readily biodegradable in the environment, likely to persist in soil and water
Bioaccumulative Potential: Moderate potential, based on chemical structure
Mobility in Soil: May demonstrate partial mobility; soil binding anticipated for some fraction
Other Adverse Effects: Hazard to aquatic ecosystems, users must avoid uncontrolled release
Waste Disposal Methods: Dispose of as hazardous pharmaceutical waste in accordance with all applicable local, regional, and national laws
Contaminated Packaging: Clean thoroughly before reuse or offer for recycling if possible, otherwise treat packaging as hazardous waste
Special Precautions: Do not allow product or wash water to enter drains, ditches, or watercourses
UN Number: Not classified as dangerous for transport under UN, ADR/RID, IMDG, or IATA regulations
Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: Not designated as marine pollutant
Special Transport Precautions: Avoid conditions that can lead to leakage or spillage, transport in secure containers
U.S. Federal Regulations: Not subject to reporting requirements under CERCLA, SARA Title III
TSCA Status: Not listed for non-research applications
EU Regulations: Classified as hazardous under CLP Regulation (EC) No 1272/2008
Other International Regulations: Subject to regulation as a prescription pharmaceutical product
Specified Restrictions: Use restricted to authorized personnel, registration and documentation necessary for manufacturing and distribution
