Product Name: Creatine Ethyl Ester Malate
Chemical Formula: C8H17N3O2•C4H6O5
Synonyms: CEE Malate, Creatine Ester Malate
Recommended Use: Nutrition supplement ingredient
Manufacturer’s Details: Contact supplier for specifics
Emergency Contact: Refer to local emergency services or Poison Control
Hazard Classification: Not classified as hazardous according to GHS criteria
Potential Health Effects: May cause mild irritation to eyes and skin on contact; inhalation of dust may trigger respiratory discomfort
NFPA Rating: Health: 1, Flammability: 0, Reactivity: 0
Label Elements: None required under standard GHS
Precautionary Statements: Avoid breathing dust; use personal protective equipment when handling powder and during cleanup
Component: Creatine Ethyl Ester Malate
CAS Number: 223235-97-6
Concentration: ≥ 95%
Impurities: Trace byproducts (unreacted creatine, ethyl ester, malic acid; collectively < 5%)
Eye Contact: Flush with lukewarm water for at least fifteen minutes, hold eyelids open; seek medical attention if irritation lingers
Skin Contact: Remove contaminated clothing, wash skin with soap and water; get medical help for persistent redness or rash
Inhalation: Move to fresh air; seek attention if breathing becomes difficult or cough persists
Ingestion: Rinse mouth; drink water to dilute; seek medical evaluation if feeling unwell
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray
Unsuitable Extinguishing Media: Direct water jets (avoid dust dispersal)
Hazards from Combustion: May emit carbon oxides and nitrogen oxides when heated intensively
Protective Equipment: Self-contained breathing apparatus, full protective gear
Firefighting Instructions: Avoid inhaling vapors or dust generated by fire conditions
Personal Precautions: Use dust mask, gloves, and eye protection
Environmental Precautions: Prevent powder from entering waterways or soil
Methods for Cleanup: Sweep up gently, minimize dust, collect in clearly labeled containers; ventilate area
Spill Handling: Dispose via approved chemical waste protocols; decontaminate area with water after removal
Handling Practices: Avoid powder generation or dust inhalation; use in ventilated areas; keep containers closed
Hygiene Measures: Wash hands thoroughly after use; avoid contact with eyes, skin, clothing
Storage Conditions: Store cool, dry, well-ventilated place away from strong oxidizers or moisture
Container Requirements: Tightly sealed, labeled, food-grade materials for bulk storage
Engineering Controls: Local ventilation or extraction to control dust
Exposure Limits: No occupational exposure limits set specifically; general nuisance dust limit < 10 mg/m3
Personal Protective Equipment: Gloves (nitrile or similar), dust mask (P2/N95), safety goggles
Workplace Hygiene: Facilities for eye/skin washing; avoid eating or smoking in work area
Physical State: Fine powder
Color: White to off-white
Odor: Practically odorless
Molecular Weight: Approx. 343.28 g/mol (combined ester and malate salt)
Melting Point: Not precisely established
Solubility: Slightly soluble in water; increases in acidic conditions
pH (in solution): Acidic (expected pH 3.5 – 4.5 for 1% solution)
Flash Point: Not applicable
Boiling Point: Data not available; decomposes
Vapor Pressure: Negligible
Density: Bulk density approx. 0.45 – 0.6 g/cm3
Chemical Stability: Stable under normal conditions, avoid high humidity
Reactivity: Reacts with strong oxidizers, acids
Conditions to Avoid: Moist environments, heat, open containers
Hazardous Decomposition: Under intense heat, may produce carbon monoxide, nitrogen oxides
Polymerization: Not expected to occur
Likely Routes of Exposure: Skin, eyes, respiratory tract
Acute Toxicity: No acute toxicity data available; low expected oral toxicity based on ingredients
Irritation: Dust may irritate respiratory tract, eyes, and skin on contact
Chronic Toxicity: Long-term effects not established; based on structure, low risk at recommended doses
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Sensitization: Not known to trigger allergic response in healthy adults
Environmental Impact: No significant issues anticipated for aquatic or terrestrial life at worksite exposure levels
Aquatic Toxicity: No measured data; high solubility could contribute to localized issues if spilled in volume
Persistence and Degradability: Biodegradable in natural conditions
Bioaccumulation: Not expected
Mobility in Soil: Moderately mobile when dissolved; best not to release in large quantities
Waste Disposal Methods: Mix with suitable absorbent and dispose via licensed waste contractor
Packaging Disposal: Can be landfilled after cleaning; recycle where possible
Precautionary Disposal: Do not incinerate in open air; avoid release into drains or surface water
Local Regulations: Observe local, state, and national environmental requirements
UN Number: Not regulated
Proper Shipping Name: Not regulated as dangerous goods
Transportation Hazard Class: N/A
Packing Group: N/A
Special Transport Notes: Handle containers carefully to avoid breakage and dust release
GHS Labeling: Non-hazardous; no symbol required
Regulatory Listings: Not listed as hazardous under major regulations (REACH, TSCA, DSL, AICS)
Occupational Safety: No unique workplace restrictions
Food Supplement Status: Subject to FDA/EFSA guidance and local/industry compliance for dietary ingredients
Community Right-to-Know: No reportable quantities; not subject to routine community release reporting
