Disodium Citrate Material Safety Data Sheet (MSDS)

Identification

Product Name: Disodium Citrate Dihydrate
Chemical Formula: C6H6Na2O7·2H2O
CAS Number: 6132-05-4
Synonyms: Citric Acid, Disodium Salt, Dihydrate; Sodium Citrate, Disodium Salt
Recommended Use: Buffer, Food additive, Analytical reagent
Supplier Address: Contact local supplier for up-to-date details
Emergency Contact: Refer to local emergency number

Hazard Identification

Classification: Not classified as hazardous according to GHS standards
Physical Hazards: Low to negligible physical risk
Health Hazards: Low toxicity; may cause mild skin or eye irritation
Environmental Hazards: Generally low concern, but large spills may affect aquatic life
Main Routes of Exposure: Inhalation, eye or skin contact, ingestion
Label Elements: No signal word, pictogram, or hazard statement required for GHS
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling

Composition / Information on Ingredients

Chemical Name: Disodium Hydrogen Citrate Dihydrate
CAS Number: 6132-05-4
Concentration: 100% (or as supplied)
Impurities/Additives: No significant impurities expected

First Aid Measures

Inhalation: Move person to fresh air, provide artificial respiration if necessary, seek medical attention for persistent symptoms
Skin Contact: Rinse with water, remove contaminated clothing, get medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, consult an eye specialist if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention if large amount swallowed or symptoms develop
Most Important Symptoms: Mild skin or eye irritation, stomach discomfort
Notes for Doctor: Treat symptomatically

Fire-Fighting Measures

Flammability: Non-flammable solid
Suitable Extinguishing Media: Use water spray, dry powder, foam or carbon dioxide
Unsuitable Extinguishing Media: None known
Special Hazards: May decompose under fire conditions, releasing irritating fumes like oxides of carbon and sodium
Protective Equipment for Firefighters: Wear full protective gear and self-contained breathing apparatus
Additional Information: Move containers from fire area if it can be done safely

Accidental Release Measures

Personal Precautions: Minimize dust formation, use personal protective equipment such as gloves, goggles, dust mask
Environmental Precautions: Keep out of water sources, avoid environmental release of large amounts
Cleaning Up: Sweep up and place into suitable container for disposal, ventilate area, wash spill site after material pickup
Disposal: Follow local and national regulations, prevent further leakage or spillage if safe to do

Handling and Storage

Safe Handling Advice: Avoid raising dust, avoid contact with skin and eyes, wash hands after use
Storage Conditions: Store in tightly closed container, keep in cool, dry and well-ventilated place
Incompatibilities: Strong acids, strong bases, moisture
Special Packaging Requirements: Use moisture-proof packaging for bulk storage

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established by OSHA, NIOSH, or ACGIH
Engineering Controls: Use local exhaust ventilation to minimize dust
Personal Protective Equipment:

  • Eyes: Safety goggles with side-shields
  • Skin: Protective gloves (nitrile, PVC, or latex)
  • Respiratory: Dust respirator if dust is generated
  • Clothing: Lab coat or protective garments to prevent skin contact
Hygiene Measures: Wash thoroughly after handling, avoid eating, drinking, or smoking around chemical

Physical and Chemical Properties

Appearance: White, crystalline powder or granules
Odor: Odorless
pH (5% solution): 7.5 – 9.0
Melting Point: ~150°C (decomposes)
Boiling Point: Not applicable
Flash Point: Not applicable
Flammability: Not flammable
Vapor Pressure: Not significant
Density: 1.7 g/cm³
Solubility in Water: Freely soluble
Partition Coefficient: Not available
Decomposition Temperature: >150°C

Stability and Reactivity

Chemical Stability: Stable under normal conditions
Reactivity: Not reactive under recommended storage and handling
Conditions to Avoid: Moisture, extreme heat
Incompatible Materials: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition Products: Carbon oxides, sodium oxides when heated to decomposition
Polymerization: Will not occur

Toxicological Information

Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Low oral toxicity (LD50 oral rat: >5000 mg/kg), no significant inhalation or dermal toxicity noted
Skin Corrosion/Irritation: May cause mild, temporary irritation
Serious Eye Damage/Irritation: May cause mild, temporary irritation
Respiratory Sensitization: Not known to be a respiratory sensitizer
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: No evidence found from available studies
Reproductive Toxicity: Not expected to cause reproductive harm
Chronic Effects: No data suggesting serious long-term effects

Ecological Information

Ecotoxicity: Low toxicity to aquatic life; large amounts may cause temporary alteration of water pH
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: No data indicating potential for significant environmental harm in standard uses

Disposal Considerations

Disposal Methods: Dispose of contents and container in accordance with local, regional, and national regulations
Container Disposal: Rinse thoroughly, offer for recycling or disposal with household waste if uncontaminated
Special Precautions: Avoid discharge into drains, water courses, or onto the ground

Transport Information

UN Number: Not applicable (not classified as dangerous for transport)
Proper Shipping Name: Disodium Citrate
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Marine Pollutant: No
Special Transport Precautions: Protect containers from physical damage and moisture during transport

Regulatory Information

TSCA Status: Listed on the United States TSCA Inventory
REACH Registration: Exempt or already registered in the EU
OSHA Standard: Not considered hazardous under OSHA Hazard Communication Standard
SARA Title III: Not regulated
California Proposition 65: Not listed
WHMIS Classification (Canada): Not hazardous
EINECS/ELINCS Number: 200-675-3
Other Regulatory Info: Meets major global food and pharmaceutical standards when sourced properly