Product Name: Ethacridine Lactate
Chemical Name: 6-Ethylaminoacridine lactate
CAS Number: 6402-23-9
Synonyms: Rivanol; Acrinol; Ethacridine Monolactate
Molecular Formula: C15H15N3O·C3H6O3
Intended Use: Antiseptic, pharmaceutical component, laboratory chemical
Manufacturer Information: [Company Contact: See regulatory documents for local details]
Emergency Phone: [Available on regulatory label or company website]
Classification: Eye Irritant, Skin Sensitizer, Harmful if Swallowed
GHS Label Elements: Warning; Harmful if swallowed; Causes serious eye irritation
Hazard Statements: May cause eye, skin, or respiratory irritation. Swallowing brings nausea, headache, and possible liver effects.
Precautionary Statements: Avoid contact with eyes and skin. Avoid inhalation of dust or fumes. Wash hands thoroughly after handling. Do not eat, drink, or smoke near workspace.
Potential Health Effects: Eye redness and watering; skin irritation; allergic reaction from repeated exposure.
Component: Ethacridine Lactate
Chemical Formula: C15H15N3O·C3H6O3
Concentration: 98–100% typical content in lab standard
Impurities: Trace organic salts, solvents under 2% total weight
Other Components: None expected under standard preparation
Eye Contact: Flush eyes with lukewarm water for at least 15 minutes, lifting eyelids to ensure thorough cleansing; seek medical help if irritation persists.
Skin Contact: Remove contaminated clothing and wash skin with soap and water; see a healthcare provider if symptoms last.
Inhalation: Move person to fresh air; if trouble breathing, medical attendance required.
Ingestion: Rinse mouth thoroughly; do not induce vomiting. Provide water to drink. Fetch medical attention for significant quantities.
Important: Always consult a medical provider, bring this safety sheet along.
Suitable Extinguishing Media: Use dry chemical, CO2, foam, or water spray.
Specific Hazards: Product may emit acrid smoke, nitrogen oxides, and carbon oxides when burning.
Protective Equipment: Firefighters use self-contained breathing apparatus and protective clothing. Avoid smoke exposure.
Firefighting Precautions: Cool containers exposed to flame using water spray. Clear out area and ventilate after fire control.
Personal Precautions: Avoid dust formation, wear appropriate gloves and eye protection.
Spill Procedures: Sweep spilled material carefully into closable container, avoid generating dust, ventilate spill area.
Environmental Precautions: Prevent entry to watercourses, drains, and soil. Notify authorities if large spill contaminates the environment.
Clean-up: Wash spill site after material pickup. Remove contaminated clothing, wash before re-use.
Handling: Use with adequate ventilation, minimize dust generation, handle only in designated chemical workspaces.
Safe Practices: Wear personal protective equipment, keep container closed unless in use.
Storage Conditions: Store in a cool, dry place away from moisture, incompatible materials such as strong oxidizers or acids, light-protected containers.
Storage Labeling: Clear labeling required. Secure away from children and untrained handlers.
Occupational Exposure Limits: PEL/TLV not established for this compound. Practice general threshold limit for dust, total inhalable fraction 10 mg/m³.
Eye Protection: Chemical safety goggles.
Skin Protection: Lab coat, gloves resistant to chemicals (latex, nitrile, or neoprene suggested).
Respiratory Protection: Dust mask if work creates airborne material; use approved respirator for large-scale accidental release.
Engineering Controls: Chemical fume hood, local exhaust ventilation.
Hygienic Practices: Wash hands after handling and before meals; keep work area clean.
Appearance: Yellow crystalline powder
Odor: Odorless or very faint organic scent
pH: Solution near neutral; 5.5–7.5
Melting Point: 124–128°C (compound); decomposition possible at higher range
Boiling Point: Not applicable (decomposes on heating)
Solubility: Soluble in water, less in alcohol
Vapor Pressure: Not measurable at ambient conditions
Density: ~1.35 g/cm³ at room temperature
Partition Coefficient: logP (estimated) 0.8–1.2
Other Data: Not flammable; stable under recommended use.
Stability: Stable under typical storage and use conditions.
Reactive With: Strong oxidizing agents, strong acids.
Decomposition: Forms toxic gases (NOx, CO, CO2) at higher temperatures.
Incompatible Conditions: Heat, light, moisture, and storage with oxidizers may cause degradation.
Polymerization: Will not occur.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Effects: Irritation of eyes, skin; nausea and stomach pain possible on swallowing.
Chronic Effects: No clear data on repeated exposure, but some risk of dermatitis or allergic reaction.
Oral LD50 (rat): 1200–1300 mg/kg
Skin Sensitization: Possible in sensitive individuals.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No findings in current studies to suggest significant risk at recommended exposure.
Aquatic Toxicity: Not classified as highly toxic to aquatic organisms, though large amounts may negatively affect algae, daphnia, or fish.
Persistence and Degradability: Likely to persist in aquatic environments; slow biodegradation.
Bioaccumulative Potential: Low, based on chemical structure.
Mobility in Soil: Moderate, water-soluble fraction may migrate in soil.
Other Adverse Effects: Avoid direct release to environment; monitor effluent carefully in pharmaceutical or industrial settings.
Recommended Disposal: Collect residue and sweepings for chemical waste disposal. Do not dispose in household garbage or untreated drains.
Disposal Containers: Clearly marked, compatible containers, handled by licensed chemical disposal contractor.
Disposal regulations: Follow local, regional, and national hazardous waste requirements.
UN Number: Not listed in the primary international transport listings
Transport Classification: Not regulated under ADR/RID, IMDG, IATA as a dangerous good
Special Transport Measures: Avoid physical damage to package, transport in sealed, labeled containers. Keep dry and cool.
Environmental Hazards: Not defined as marine pollutant; avoid carrying with oxidizing agents.
Inventory Listings: Substance listed in relevant chemical inventories (TSCA, EINECS, etc.)
Signal Word: Warning (GHS)
Hazard Codes: Xn (Harmful), Xi (Irritant)
Risk Phrases: R22 (Harmful if swallowed), R36/37/38 (Irritating to eyes, respiratory system, and skin)
US Regulatory Status: Not regulated as a hazardous substance under SARA Title III, CERCLA, not on Proposition 65
EU Regulatory Status: Not classified as a priority risk under REACH restrictions.
Labelling: Comply with local label rules for workplace hazardous material.
