Product Name: Halofuginone Lactate
Chemical Formula: C16H17ClN3O3•C3H6O3
CAS Number: 64924-67-0
Manufacturer: Details typically straight from the supplier’s documentation
Intended Use: Veterinary medication, coccidiostat in livestock, research
Contact for Emergency: Refer to local poison control or emergency contacts
Synonyms: Halofuginone hydrolactate, STENOROL
Recommended Restrictions: Professional use in controlled industrial or agricultural settings
Packaging: Usually packed in sealed containers, often as powder or granules
Hazard Classification: Toxic if swallowed; respiratory and skin sensitizer; category 3 acute toxicity
GHS Symbol: Skull and crossbones, exclamation mark
Signal Word: Danger
Hazard Statements: May cause allergy or asthma symptoms; serious eye irritation; harmful to aquatic life
Potential Health Effects: Respiratory tract irritation, dermal sensitization, gastro-intestinal upset on ingestion
Environmental Hazards: Toxic to aquatic organisms and may cause long-lasting effects in water
Specific Target Organ Toxicity: Repeated exposure can damage muscle and connective tissue in large mammals
Precautionary Statements: Wear protective gloves, avoid release to environment, seek medical advice after exposure
Chemical Name: Halofuginone Lactate
CAS Number: 64924-67-0
Percentage: Pure substance; for formulated products, can vary between 0.1% and 10%
Impurities: Minor unreacted starting materials, possible trace solvents
Stabilizers and Additives: May include lactose, sodium starch glycolate, and magnesium stearate, depending on formulation
Other Ingredients: Fillers and binders in veterinary additives or feed supplements
Inhalation: Move exposed person to fresh air; seek medical care if breathing difficulty or irritation appears; administer oxygen if symptoms persist
Skin Contact: Remove contaminated clothes; wash skin thoroughly with soap and water; seek medical attention if irritation or rash develops
Eye Contact: Flush eyes immediately with water for at least 15-20 minutes; lift eyelids to ensure thorough rinsing; get medical attention promptly
Ingestion: Do not induce vomiting; rinse mouth with water; give water only if person is fully conscious; seek urgent medical help
Most Important Symptoms: Breathing problems, burning sensation, severe gastrointestinal discomfort
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Inappropriate Extinguishing Media: Avoid direct water jets that may spread material
Hazards From Combustion: Toxic fumes such as nitrogen oxides, chlorine-containing gases, carbon monoxide, carbon dioxide
Protective Gear: Full protective firefighting suits, self-contained breathing apparatus
Specific Fire Procedures: Cool containers with water spray from a safe distance; move containers away from fire if safe to do so
Personal Precautions: Use respiratory protection, chemical-resistant gloves, and splash-proof goggles
Environmental Precautions: Prevent spread to soil, drains, or water bodies; contain spillage using inert absorbent
Spill Cleanup Methods: Scoop or sweep up spilled powder and place in sealed, labeled containers; clean area with water and detergent
Disposal of Contaminated Materials: Treat as hazardous waste; follow local disposal laws; avoid creating airborne dust
Decontamination: Wash surfaces and tools with soapy water after cleanup
Handling: Avoid breathing dust or vapors; prevent contact with skin and eyes; use in well-ventilated spaces with appropriate safety equipment
Storage: Store in original, tightly-sealed containers in a cool, dry, well-ventilated area; keep away from food, feedstuffs, acids, and oxidizers
Storage Temperature: Stable at room temperature; avoid freezing or exposing to excessive heat
Special Storage Instructions: Secure containers upright; keep out of reach of children and animals
Incompatible Materials: Strong acids, alkalis, oxidizing agents
Engineering Controls: Use local exhaust ventilation or fume hoods to minimize airborne dust
Personal Protection: NIOSH-approved respirator, chemical-resistant gloves (nitrile or neoprene), laboratory coat or apron, closed footwear, splash-proof goggles
Hygiene Measures: Wash thoroughly after handling; remove contaminated clothing and wash before reuse; do not eat, drink, or smoke during use
Exposure Limits: No specific occupational exposure limits set; use good laboratory/industrial hygiene practices
Environmental Controls: Prevent runoff or contamination of drains and waterways
Appearance: White to off-white crystalline powder
Odor: No significant odor
Odor Threshold: Not established
pH: 4.0-6.0 (1% aqueous solution)
Melting Point: 212-215°C
Boiling Point: Not applicable, decomposes before boiling
Flash Point: Not combustible under typical conditions
Solubility: Soluble in water, sparingly soluble in ethanol and methanol
Vapor Pressure: Negligible
Partition Coefficient (log Kow): Not available
Stability in Water: Stable
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen chloride gas under fire
Chemical Stability: Stable under normal temperatures and pressures
Conditions to Avoid: Exposure to high heat, sunlight, moisture, and incompatible materials
Materials to Avoid: Strong acids, alkalis, oxidizers
Hazardous Decomposition: Releases toxic gases in case of fire or excessive heating
Polymerization: Will not undergo hazardous polymerization under recommended conditions
Acute Toxicity: Oral LD50 for rats: between 2-20 mg/kg; toxic if ingested
Inhalation Effects: Respiratory tract irritation, shortness of breath, coughing
Dermal Effects: May cause sensitization or allergic reactions; mild to moderate skin irritation on repeated exposures
Ocular Effects: Causes eye irritation, redness, watering
Chronic Toxicity: Subchronic exposure in animals linked to tissue lesions
Carcinogenicity: Not classified as carcinogenic by IARC/NTP/OSHA
Mutagenicity: No evidence reported
Reproductive Toxicity: High exposure in animal studies leads to developmental toxicity
Toxicity to Aquatic Life: Highly toxic to fish, daphnia, and other aquatic organisms
Persistence and Degradability: Not readily biodegradable; persistent in environment, risk of accumulation
Mobility in Soil: Moderately mobile; risk of groundwater contamination
Bioaccumulation Potential: Evidence of moderate potential for bioaccumulation in aquatic life
Aquatic Chronic Effects: Long-term exposure hazardous to aquatic plants and invertebrates
Disposal Methods: Chemical waste incineration in approved facilities
Waste Code: Specific code depends on local laws
Container Disposal: Rinse empty containers, puncture to prevent re-use, dispose in agreement with regional hazardous waste regulations
Special Instructions: Do not mix with regular garbage or pour into sewage or water bodies
Spilled Product: Collect and store for disposal, avoid dust generation
UN Number: Consult regulatory transport lists
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains halofuginone lactate)
Transport Hazard Class: Class 6.1 (Toxic substances)
Packing Group: II or III, depending on concentration
Label Requirements: ‘Toxic’ symbol, warning notices
Special Transport Precautions: Secure in sealed, labeled containers; avoid damaging packaging during loading and unloading
Marine Pollutant: Yes
TSCA Status: Not listed for general public use in United States
EU Regulation: Covered by REACH regulation for industrial and veterinary chemicals
OSHA Status: Considered hazardous under OSHA definitions for occupational exposure
WHMIS Classification (Canada): Toxic Material
Other National Inventories: Listed in Australia AICS, not routinely listed in most consumer inventories
Other Regulations: Permitted for use as a coccidiostat in certain countries with veterinary supervision; restricted use in food-producing animals under veterinary prescription
Precautionary Legislation: Use under regulated conditions, subject to monitoring of environmental emissions and residues in animal products
