Product Name: Lithium Citrate Tetrahydrate
Chemical Formula: C₆H₅Li₃O₇·4H₂O
CAS Number: 6080-58-6
Synonyms: Trisodium-2-hydroxypropane-1,2,3-tricarboxylate lithium salt, Lithium tricarballylate tetrahydrate
Product Use: Laboratory reagent, pharmaceutical applications, chemical synthesis
Manufacturer: [Company Name]
Emergency Contact: [Emergency Phone Number]
GHS Classification: Acute Toxicity – Oral (Category 4), Eye Irritation (Category 2A), Skin Irritation (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or fumes. Wear protective gloves and eye protection. Wash hands thoroughly after handling. Do not eat, drink, or smoke near material.
Symptoms of Exposure: Sore throat, abdominal pain, headache, skin redness, eye redness and watering
Substance: Lithium Citrate Tetrahydrate
Concentration: >98%
Chemical Identity: Lithium citrate with four molecules of water
Impurities: Trace levels of lithium carbonate, water-insoluble residues (less than 1%)
Inhalation: Move person to fresh air. Seek medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing. Wash area thoroughly with soap and water for 15 minutes. Contact physician if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if easily possible. Continue rinsing and get medical help if discomfort lingers.
Ingestion: Rinse mouth with water. Do not induce vomiting. Get medical attention. If feeling unwell, call Poison Control or a doctor right away.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Specific Hazards: Emits toxic fumes under fire conditions (lithium oxides, carbon oxides). Potent irritant smoke risk.
Protective Equipment: Firefighters need full protective gear and self-contained breathing apparatus.
Hazardous Combustion Products: Carbon oxides, lithium oxides.
Advice for Firefighters: Approach fire from upwind. Prevent entry of runoff to water sources.
Personal Precautions: Keep away from dust, wear gloves, safety goggles, and dust mask. Prevent skin and eye contact.
Environmental Precautions: Block spills from entering drains, surface water, or soil.
Methods for Cleaning Up: Collect using inert absorbent material. Sweep up, shovel, and place in marked container. Wash area thoroughly after cleanup. Dispose of cleanup waste by local regulations.
Handling: Handle in a well-ventilated place. Avoid dust formation. Do not get on skin, eyes, or clothing. Use suitable protective equipment and avoid eating or drinking around material.
Storage: Keep container tightly closed in a cool, dry place. Store away from acids and oxidizing agents. Label storage containers clearly. Prevent moisture contact by sealing containers after use.
Control Parameters: No established occupational exposure limits for lithium citrate. Maintain low airborne concentration.
Engineering Controls: Work in fume hood or under local exhaust. Use ventilation to keep dust levels low.
Personal Protection: Wear chemical-resistant gloves, protective eyewear, lab coat, and dust mask. Clean hands after handling.
Hygiene Measures: Set aside contaminated clothes for washing before reuse. Practice good personal hygiene.
Appearance: White crystalline powder
Odor: Odorless
pH (10% solution): 7.5 – 9.0
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Solubility: Soluble in water
Density: Approx. 1.5 g/cm³
Vapor Pressure: Not applicable
Flash Point: Not flammable
Partition Coefficient (n-octanol/water): Data not available
Evaporation Rate: Not relevant for solid
Chemical Stability: Stable under standard conditions if kept dry and sealed.
Reactivity: Reacts with strong acids to produce heat and lithium salts.
Conditions to Avoid: Exposure to moisture, sources of ignition, and incompatible substances.
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition Products: Lithium and carbon oxides released at high temperatures.
Polymerization: Not expected to occur
Acute Toxicity: Harmful if swallowed; estimated oral LD₅₀ for rats in range of 500–2000 mg/kg.
Skin Irritation: Repeated or prolonged contact causes reddening and injury.
Eye Damage: Strong irritant, causes tearing and burning sensations.
Chronic Effects: Prolonged ingestion can affect kidney, thyroid, and nervous system. Lithium compounds influence central nervous system and electrolyte balance.
Carcinogenicity: Not listed as a known carcinogen.
Sensitization: Not reported.
Mutagenic Effects: No available data.
Reproductive Toxicity: Possible, based on effects of some lithium compounds in animal studies.
Ecotoxicity: Toxic to some aquatic organisms. Data limited, but lithium ions found to impair fish and daphnia at elevated levels.
Persistence and Degradability: Not expected to biodegrade in environment; dissociates to ions.
Bioaccumulation: Not likely to accumulate in aquatic life.
Mobility in Soil: Soluble and mobile in water, possible groundwater contamination if released.
Additional Notes: Prevent spillage; do not release to waterways or soil.
Waste Disposal Methods: Dispose of as hazardous chemical waste. Use sealed, labeled containers for discards.
Contaminated Packaging: Rinse and dispose of container as hazardous waste.
Local Regulations: Follow national, regional, and local rules for lithium compound disposal.
Precautions: Do not dump into sewer, soil, or surface waters.
UN Number: Not regulated for transport in most regions.
Proper Shipping Name: Lithium Citrate Tetrahydrate
Hazard Class: Non-hazardous for air and ground shipment under standard guidelines.
Packing Group: Not assigned
Labels: Not required, unless bundled with other hazardous materials.
Environmental Hazards: Not marine pollutant
Transport Precautions: Protect packaging from damage and moisture.
Labelling: GHS-compliant labeling with hazard and precautionary statements.
Inventory Status: Listed in TSCA (USA), REACH (EU), DSL (Canada).
SARA Title III: Not listed under Sections 302/304/313 as an extremely hazardous substance.
California Prop 65: No chemicals known to cause cancer or reproductive toxicity present.
WHMIS (Canada): D2B – Toxic material causing other toxic effects.
Other Information: Safety training for all handlers is advised. Review and update this sheet with any regulatory changes.
