Product Name: Magnesium Citrate Malate
Chemical Formula: C12H10O14Mg3
CAS Number: 144-23-0 (for magnesium citrate); 6712-89-2 (for magnesium malate)
Intended Use: Nutritional supplement, laboratory reagent
Synonyms: Magnesium tricarboxyethyloxy propane, Trimagnesium bis(2-hydroxybutanedioate) citrate
Manufacturer Name: Manufacturer details must be provided on product label
Emergency Contact: Refer to local Poison Control Center or emergency hotline
GHS Classification: Not classified as hazardous under GHS criteria for magnesium citrate malate in food or supplement grade
Hazard Statements: Dust may cause temporary mild respiratory irritation
Signal Word: None required for most consumer-grade products
Pictograms: No pictograms assigned for non-industrial handling
Precautionary Statements: Avoid creating dust, prevent eye contact, avoid inhalation, keep container tightly closed
Potenial Effects: Dust may irritate nose, throat, or eyes in sensitive individuals; ingestion in excess may lead to gastrointestinal upset
Ingredient: Magnesium Citrate Malate
Chemical Identity: Mixture of magnesium citrate and magnesium malate (ratio varies by manufacturer)
Purity: Typically ranges from 95% to 99% active ingredient
Impurities: Less than 1% — includes trace minerals or inert fillers common to nutritional formulations
Other Components: Water of hydration, if present, constitutes minor percentage
Inhalation: Move to fresh air, seek medical advice if breathing becomes difficult or symptoms persist
Skin Contact: Rinse with water and mild soap, remove contaminated clothing, seek medical attention if redness or irritation develops
Eye Contact: Flush with copious amounts of water for at least 15 minutes, remove contact lenses if present and easy to do, seek attention for persistent discomfort
Ingestion: Rinse mouth with water, drink water to dilute, seek medical advice for large ingestion or significant symptoms such as abdominal pain or diarrhea
Special Advice for Doctors: Symptomatic treatment recommended, monitor for electrolyte imbalance in large ingestions
Suitable Extinguishing Agents: Use water spray, CO2, dry chemical, or foam
Unsuitable Media: No known unsuitable types for this material
Hazardous Combustion Products: Carbon oxides, possible magnesium oxide fumes
Protective Equipment: Wear full protective gear including NIOSH-approved self-contained breathing apparatus, if risk of dust or fume exposure
Special Fire Procedures: Avoid inhaling fumes, isolate area, ventilate after extinguishing
Personal Precautions: Wear dust mask or respirator, use protective goggles, avoid breathing dust, avoid contact with skin and eyes
Environmental Precautions: Prevent spillage from entering water courses, drains, or soil
Clean-Up Methods: Sweep up dry material, place in suitable labeled container, avoid generating dust, clean surfaces with water after complete removal
Disposal: Collect waste for proper disposal according to local, state, or national regulations
Incident Reporting: Report significant spills to appropriate environmental agency
Handling Precautions: Use in well-ventilated area, minimize dust generation, handle with clean, dry hands or tools, never consume in manufacturing area
Safe Storage Conditions: Store in tightly sealed container in cool, dry location, keep away from incompatible substances such as strong acids or oxidizing agents
Separation: Avoid storage with strong mineral acids, do not store near odorous or volatile chemicals that may contaminate product
Other Recommendations: Label containers clearly, rotate stock to ensure freshness, keep out of reach of children
Engineering Controls: Maintain adequate ventilation, use local exhaust in large-scale operations
Personal Respiratory Protection: Use dust respirator or mask when handling large quantities or in dusty environments
Eye Protection: Safety glasses or goggles recommended where dust risk exists
Skin Protection: Use gloves for prolonged or repeated handling, wash hands after use
Exposure Limits: No established OSHA, NIOSH, or ACGIH exposure limits for magnesium citrate malate, treat as nuisance dust (recommended limit: 10 mg/m3 total, 5 mg/m3 respirable fraction)
Appearance: White to off-white powder, crystalline
Odor: Odorless or very faint, characteristic taste in solution
Odor Threshold: Not applicable
pH (1% Solution): Typically 4.0 to 6.0
Melting Point/Range: Decomposes above 200°C
Boiling Point/Range: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Evaporation Rate: Not volatile
Flammability: Not classified as flammable
Vapor Pressure: Not volatile
Density: Approximately 1.5–2.0 g/cm³
Solubility: Soluble in water, slightly soluble in alcohol
Partition Coefficient: Not determined
Auto-Ignition Temperature: Not applicable
Decomposition Temperature: >200°C
Viscosity: Not applicable
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Low chemical reactivity in ambient conditions
Conditions to Avoid: Exposure to high moisture or humidity, excessive heat, strong acids or strong oxidizers
Incompatible Materials: Strong mineral acids, strong oxidizing agents, alkali metals may react with evolved gases
Hazardous Decomposition Products: Carbon oxides, magnesium oxide, possibly formic acid under combustion
Polymerization: Will not occur
Likely Routes of Exposure: Inhalation, ingestion, skin or eye contact (main risks occur with large-scale or industrial exposure)
Acute Toxicity: Not known to be acutely toxic, oral LD50 (rat) > 2000 mg/kg based on component data
Chronic Toxicity: No known chronic effects for general population in normal dietary usage, excess doses could lead to diarrhea or electrolyte imbalance
Skin Irritation: Not irritant under normal conditions
Eye Irritation: May cause transient discomfort if dust contacts eyes
Respiratory Sensitization: Not a sensitizer
Carcinogenicity: No components are listed as carcinogens by IARC, NTP, OSHA, or ACGIH
Reproductive Effects: No known risk to reproduction under normal exposure; nutritional levels considered safe
Other Health Effects: Magnesium supplementation in excess can cause gastrointestinal upset, hypermagnesemia in susceptible individuals
Ecotoxicity: Low environmental toxicity expected due to bioavailability of magnesium as an essential element
Aquatic Toxicity: No acute toxicity observed for freshwater or marine organisms at expected concentrations
Persistence and Degradability: Readily biodegradable, dissociates into naturally occurring ions
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Dissolves and is transported through soil, becomes part of natural magnesium and organic acid cycles
Other Adverse Effects: Large spills in water systems may cause temporary pH shifts
Waste Handling: Dispose of in accordance with federal, state, and local environmental control regulations
Recommended Method: For small amounts, wash away with large quantities of water, ensure effluents discharged to permitted sanitary systems
Large Quantities: Collect and deliver to licensed waste disposal contractor
Packaging Disposal: Rinse containers thoroughly before recycling or disposal, do not reuse for food or drink
Regulatory Classification: Generally non-hazardous waste, always verify local waste classification for specific forms
UN Number: Not regulated
UN Proper Shipping Name: Not classified as a hazardous material for transportation
Hazard Class: None assigned
Packing Group: None assigned for supplement or food grade magnesium citrate malate
Special Transport Precautions: Use sealed, clearly labeled containers, protect against moisture and physical damage
Inventory Status: Magnesium citrate and magnesium malate are listed in chemical inventories such as US TSCA, EU REACH, Australia AICS
Labeling Requirements: No hazardous labeling required under current OSHA, EU, or GHS standards unless intended for industrial/chemical use
Food/Pharma Regulations: Recognized as Generally Recognized As Safe (GRAS) by FDA at nutritional supplement levels
Other Regulations: Not regulated as a controlled substance in any major jurisdictions, but purity and labeling for supplements must comply with relevant standards such as USP, FCC, or EFSA regulations
