Product Name: Trimethyl Citrate
Chemical Formula: C9H14O7
Synonyms: Citric acid, trimethyl ester; Methyl citrate
CAS Number: 1587-20-8
Manufacturer: Commercial producers include chemical suppliers worldwide
Recommended Use: Plasticizer, pharmaceutical excipient, specialty chemical
Emergency Contact: Refer to local regulatory agency or Poison Control Center
GHS Classification: Not classified as hazardous under GHS criteria
Signal Word: None
Hazard Statements: May cause mild eye and skin irritation with direct contact; inhalation of dust or aerosol possible, may irritate respiratory tract
Pictogram(s): None required
Precautionary Statements: Avoid inhaling dust, wear protective gloves and safety glasses during handling, wash thoroughly after handling, avoid contact with skin and eyes
Substance: Trimethyl Citrate
Chemical Identity: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trimethyl ester
Percentage: 100% (pure compound, no known impurities relevant to classification)
Inhalation: Move person to fresh air, seek medical attention for persistent discomfort, remove source of exposure
Skin Contact: Wash skin thoroughly with soap and water, remove contaminated clothing, consult physician if irritation develops
Eye Contact: Flush with clean water for several minutes, hold eyelids open, remove contact lenses, seek medical attention if symptoms persist
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice, do not give anything by mouth to an unconscious person
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Fire Hazards: Combustion may produce carbon oxides; product is not highly flammable, but dust can present explosion risk if dispersed in air
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Special Precautions: Use water spray to cool containers exposed to fire; avoid release of smoke and combustion products into environment
Personal Protection: Wear appropriate personal protective equipment (gloves, goggles, dust mask)
Spill Response: Contain spilled material, avoid generating dust, sweep up using methods that minimize dust formation, collect in appropriate containers for disposal
Environmental Protection: Prevent entry into drains, watercourses or soil; in case of large spill, notify authorities
Cleaning Methods: Wash spill site with plenty of water after removal of residues
Handling Precautions: Keep containers tightly closed, handle in well-ventilated areas, avoid inhalation of dust or vapor, wear protective equipment
Storage Conditions: Store in a cool, dry place away from direct sunlight, sources of ignition, strong acids and oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids
Hygiene Measures: Wash hands after handling, remove contaminated clothing before entering eating areas
Occupational Exposure Limits: No ACGIH or OSHA limits established
Engineering Controls: Use local exhaust ventilation if dust is generated, general room ventilation
Personal Protective Equipment: Wear protective gloves, chemical goggles, dust mask or respirator (P2 or higher), protective clothing if necessary
Environmental Controls: Minimize dust release to environment, avoid waterway contamination
Appearance: White crystalline solid or powder
Odor: Slight, ester-like
pH: Not applicable (insoluble in water)
Melting Point: 153-156°C
Boiling Point: Decomposes before boiling
Flash Point: 190°C (estimated)
Solubility: Insoluble in water, soluble in alcohol and most organic solvents
Vapor Pressure: Negligible at 20°C
Density: Approximately 1.27 g/cm³
Partition Coefficient (log Kow): Estimated 0.1-1 (low)
Auto-ignition Temperature: No data available
Evaporation Rate: Not applicable
Chemical Stability: Stable under normal conditions of storage and handling
Conditions to Avoid: Excess heat, open flame, moisture
Incompatible Materials: Strong oxidizing agents, concentrated acids
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, other organic vapors on thermal decomposition
Polymerization: Will not occur
Acute Toxicity: Low acute toxicity expected; estimated oral LD50 for rats above 5000 mg/kg
Skin Irritation: Low to moderate; possible mild irritation with prolonged contact
Eye Irritation: Possible mild irritation
Inhalation: Dust may irritate mucous membranes and respiratory tract
Sensitization: Not known to cause allergic reactions
Chronic Toxicity: No evidence of long-term toxicity from available studies
Mutagenicity/Carcinogenicity: No evidence of mutagenicity or carcinogenicity
Ecotoxicity: Not expected to present acute hazard to aquatic organisms; low toxicity in aquatic and terrestrial environments
Degradability: Readily biodegradable, undergoes hydrolysis to citric acid and methanol
Bioaccumulation: Low potential due to high water solubility of metabolites, low partition coefficient
Mobility in Soil: Breakdown products may migrate in soil; low risk of bioaccumulation
Waste Disposal Methods: Dispose as non-hazardous organic chemical waste in accordance with local, regional, and national regulations; send to approved landfill or incineration facility
Container Disposal: Triple rinse empty containers, recycle or dispose of containers according to regulations
Special Precautions: Do not release into waterways, sewers, or soil; avoid incinerating product with halogenated materials
UN Number: Not regulated for transport
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned
Environmental Hazard: None known
Special Precautions for Transport: Protect from physical damage and moisture during transit
Labeling: No hazard labeling required under GHS or EU CLP for this compound
TSCA: Listed
REACH: Not subject to registration due to tonnage or use exemptions
DSL/NDSL (Canada): Listed
Australian AICS: Listed
Other Inventories: Included in major chemical inventories worldwide
Regulatory Restrictions: No known restrictions in major regions as of knowledge available in 2024
