Product Name: Zinc Citrate Dihydrate
Chemical Formula: C6H6O7Zn2·2H2O
CAS Number: 14221-02-4
Synonyms: Trizinc dicitrate dihydrate, Zinc citrate, Dihydrate
Recommended Use: Dental care, nutritional supplement, industrial applications
Supplier: Contact details of manufacturer/distributor
Emergency Number: Local poison control center/medical assistance line
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute aquatic toxicity (Category 1)
Label Elements: Signal word: Warning; Hazard pictograms: Exclamation mark, Environment
Hazard Statements: Causes skin irritation; Causes serious eye irritation; Toxic to aquatic life
Precautionary Statements: Wash hands thoroughly after handling; Avoid release to the environment; Use personal protective equipment
Route of Exposure: Inhalation, ingestion, eye or skin contact
Symptoms: Redness, discomfort, watering of eyes, possible skin rash, stomach upset
Chemical Name: Zinc Citrate Dihydrate
Chemical Formula: C6H6O7Zn2·2H2O
CAS Number: 14221-02-4
Weight Percentage: Approximately 100%
Impurities: None significant within current safety guidelines
Inhalation: Move person to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash immediately with soap and water, remove contaminated clothing, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice
Advice to Doctor: Treat symptomatically based on patient’s condition
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: None known for this product
Specific Hazards: Emits fumes of zinc and citric acid when heated strongly
Protective Equipment and Precautions: Firefighters wear self-contained breathing apparatus and full protective gear; prevent run-off from entering drains
Hazardous Combustion Products: Zinc oxide, carbon monoxide, carbon dioxide
Personal Precautions: Use personal protective equipment, avoid breathing dust, ensure adequate ventilation
Environmental Precautions: Prevent entry into waterways, drains, and soil
Methods for Cleaning Up: Sweep up and place in suitable containers for disposal; avoid creating dust; ventilate area
Reference to Other Sections: Refer to exposure controls and disposal guidance
Safe Handling: Minimize dust generation, keep container tightly closed, wear protective clothing, avoid contact with skin, eyes, and clothing
Storage Conditions: Store in original container in a cool, dry, well-ventilated area, away from incompatible materials such as acids and strong oxidizers
Incompatible Materials: Strong acids, strong oxidizing agents
Packing Materials: Use containers made of suitable, corrosion-resistant materials
Occupational Exposure Limits: Zinc compounds as Zn (TLV: 2 mg/m3 inhalable dust, 10 mg/m3 ceiling limit for fume)
Engineering Controls: Provide local exhaust ventilation, general mechanical ventilation
Personal Protective Equipment: Protective gloves (nitrile or PVC), safety goggles, dust mask or respirator (P2 or N95), lab coat, closed shoes
Hygiene Measures: Wash hands before eating, drinking, or smoking; remove contaminated clothing and equipment before entering eating areas
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (1% Solution): 6–8
Melting Point/Freezing Point: Decomposes
Boiling Point: Not applicable (decomposes prior to boiling)
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Non-flammable
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Solubility: Slightly soluble in water
Partition Coefficient (n-octanol/water): Data not available
Decomposition Temperature: Above 212°C (loss of water of hydration)
Molecular Weight: 574.18 g/mol
Chemical Stability: Stable under recommended handling and storage conditions
Possibility of Hazardous Reactions: No dangerous reactions known under normal use
Conditions to Avoid: High temperatures, exposure to acids or oxidizers
Incompatible Materials: Acids, strong oxidizing agents
Hazardous Decomposition Products: Zinc oxide, carbon dioxide, carbon monoxide
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Low oral toxicity; LD50 (oral, rat) estimated >2000 mg/kg
Skin Corrosion/Irritation: May cause mild to moderate irritation upon prolonged exposure
Serious Eye Damage/Irritation: May cause irritation and redness
Respiratory Sensitization: Potential for irritation at high airborne concentrations
Chronic Effects: No known significant long-term effects from normal exposure; excessive chronic zinc exposure can interfere with copper absorption
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not listed by IARC, NTP, ACGIH, or OSHA, and no evidence of mutagenicity or reproductive toxicity
Other Information: No specific data available on reproductive or developmental toxicity for this substance
Toxicity to Aquatic Life: Highly toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments; EC50 (Daphnia magna, 48hr): ~0.15 mg/L (Zinc ion basis)
Persistence and Degradability: Zinc compounds persist in the environment; citrate portion is biodegradable
Bioaccumulation Potential: Zinc accumulates in aquatic organisms, particularly fish and invertebrates
Mobility in Soil: Zinc compounds can migrate through soil and possibly reach groundwater; solubility increases in acidic conditions
Other Adverse Effects: Zinc can disrupt microbial processes in soil and water
Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, and national regulations
Waste Classification: Classified as hazardous waste due to aqua-toxicity in some jurisdictions
Contaminated Packaging: Rinse thoroughly before disposal or reconditioning; manage as hazardous waste if residue remains
Special Precautions: Do not dispose of into surface water or drains; avoid contamination of the environment
UN Number: Not regulated as dangerous goods under ADR, IMDG, or IATA
Proper Shipping Name: Zinc Citrate Dihydrate
Transport Hazard Class: Not classified
Packing Group: Not applicable
Marine Pollutant: Yes; zinc compounds hazardous to aquatic environments
Special Transport Precautions: Prevent spillage, keep packaged in sealed, labeled containers
Inventory Status: Appears on national chemical registries such as TSCA (USA), EINECS (Europe), DSL (Canada)
Labelling: Follows requirements for hazardous substances; environmental and health warnings on primary packaging
OSHA Regulatory Status: Not specifically regulated, but general duty clause applies for workplace safety
REACH Status: Registered or exempted in EU for main uses
Additional Regulations: Local and regional disposal controls, aquatic hazard labeling, environmental protection agency requirements
